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药物化学

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霍长虹博士-教授

发布时间:2016-10-29   浏览次数:0


霍长虹,博士,教授,博士生导师,best365官网登录入口天然药物化学教研室副主任。2005年毕业于北京大学获生药学博士学位。主讲本科生的天然药物化学、药学导论和研究生的中药现代化研究等课程。

主要研究方向为天然药物化学成分与活性筛选,已主持完成国家博士后科学基金、河北省自然科学基金、河北省中医药管理局、教育厅、卫生厅课题各1项,主研完成国家863课题、国家自然科学基金课题、河北省自然科学基金课题各2项。为第十届中国药学会施维雅青年药物化学奖获得者,获河北省自然科学二等奖1项,河北省中医药学会科学技术一等奖2项;中国药学会第八届全国青年药学工作者最新科研成果交流会三等奖和北京药学会“百奥杯”优秀论文一等奖各1项。


在研科研课题

作为H2S供体的天然活性α,β-不饱和倍半萜内酯的R-Sn-R(或R’)型代谢物的发现与研究,国家自然科学基金面上项目,负责人


作为第一作者或通讯作者发表的SCI论文:

[1] Phenolic components of the aerial parts of Achillea alpina. Chemistry of Natural Compounds, 2019, 55(2):337-339.

[2] A New Bisepoxylignan Glucoside from the Leaves of Forsythia suspensa. Chemistry of Natural Compounds, 2018, 54(6):1038-1040.  

[3] A chemometric-assisted LC-MS/MS method for the simultaneous determination of 17 limonoids from different parts of Xylocarpus granatum fruit. Analytical and Bioanalytical Chemistry, 2017, 409:4669?C4679.

[4] Study on the metabolites of isoalantolactone in vivo and in vitro by ultra performance liquid chromatography combined with Triple TOF massspectrometry. Food Chemistry, 2017, 214(1):328-338.

[5] Identification of in vitro and in vivo metabolites of alantolactone by UPLC-TOF-MS/MS. Journal of Chromatography B, 2016, 1033:250-260.  

[6] Polyhydroxytriterpenoids and Phenolic Constituents from Forsythia suspensa (Thunb.) Vahl Leaves. Journal of Agricultural and Food Chemistry, 2016, 64(1):125-131.

[7] Triterpenoids and Steroids from the Leaves of Forsythia suspensa. Chemistry of Natural Compounds, 2015, 51(1):178-180.  

[8] Two New Non-Taxoids from Leaves of Taxus cuspidate. Chemistry of Natural Compounds, 2014, 50(4):603-605.

[9] A New Taraxastane-Type Triterpene from the Flowers of Inula cappa. Chemistry of Natural Compounds, 2014, 50(5):850-852.

[10] Chemical Composition of Achillea alpina. Chemistry of Natural Compounds, 2014, 50(3):534-536.

[11] A New Limonoid from Xylocarpus granatum. Chemistry of Natural Compounds, 2014, 50(2): 314-316.

[12] A new glyceride from the seeds of Xylocarpus granatum. Chemistry of Natural Compounds, 2013, 48(6): 934-937.

[13] Cytotoxic flavonoids from the flowers of Achillea millefolium. Chemistry of Natural Compounds, 2013, 48(6): 958-962.

[14] Chemical Constituents of Plants from the Genus Forsythia. Mini Reviews in Organic Chemistry, 2012, 9(3):303-318.

[15] Xylocarponoids A and B, Unique 28C skeleton limonoids from Xylocarpus granatum. Tetrahedron Letters, 2010, 51(4):754-757.

[16] New neolignan glycosides and a new cerebroside from Symplocos caudata. Chem. Nat. Comp. 2010, 46(3):343-347.

[17] Two new eudesmanes from Inula helenium. Chem. Nat. Comp. 2010, 46(3):373-376.

[18] Chemical Constituents of Plants from the Genus Melia. Chemistry & Biodiversity, 2010, 7(4):839-859.

[19] Protolimonoids from the seeds of Xylocarpus granatum. Biochemical Systematics and Ecology, 2009, 37(3):218-220.

[20] Xylomexicanins A and B, New Δ14,15-Mexicanolides from Seeds of the Chinese Mangrove Xylocarpus granatum. Zeitschrift fuer Naturforschung, C, 2009, 64c (1/2):37-42.

[21] Chemical Constituents of plants from the Genus Xylocarpus. Chemistry & Biodiversity, 2009, 6(9):1293-1308.

[22] Neolignan glycosides from Symplocos caudata. Phytochemistry, 2008, 69(3):788-795.

[23] A new 5,11- Epoxymegastigmane Glucoside from Acanthus ilicifolius. Natural Product Research, 2008, 22(10):896-900.

[24] Chemical Constituents of Plants from the Genus Excoecaria. Chemistry & Biodiversity, 2008, 5(11):2356-2371.

[25] Canataxpropellane, a novel taxane with a unique polycyclic carbon skeleton (tricyclotaxane) from the needles of Taxus canadensis. Tetrahedron Letters, 2007, 48(15):2721-2724.

[26] Structural determination of a new 2(320) abeotaxane with an unusual 13-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata. Magnetic Resonance in Chemistry, 2007, 45(4):527-530.

[27] Two new taxanes from Taxus canadensis. Biochemical Systematics and Ecology, 2007, 35(12):909-913.

[28] A new taxol analogue from the leaves of Taxus cuspidata. Biochemical Systematics and Ecology, 2007, 35(10): 704-708.

[29] A New Metabolite with A New Substituted Pattern from the Seeds of the Chinese Yew, Taxus mairei. Chemistry & Biodiversity, 2007, 4(1):84-88.

[30] Chemical Constituents of Plants from the Genus Symplocos. Chemistry & Biodiversity, 2007, 4(1):1-11.

[31] Chemical Constituents of plants from the Genus Cerbera. Chemistry & Biodiversity, 2007, 4(7):1438-1449.

[32] Structure elucidation and complete NMR spectral assignments of a new benzoxazolinone glucoside from Acanthus ilicifolius. Magnetic Resonance in Chemistry. 2005, 43(4):343-345.

[33] Benzoxazinones from Acanthus ilicifolius. Biochemical Systematics and Ecology. 2005, 33(6):643-645.



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